A STUDY OF GYMNEMA SYLVESTRE AND ITS BIOACTIVE COMPONENTS EFFECT ON DIABETES MELLITUS

Author Name: 1. Snehal S. Kulkarni, 1,2. Suraj D. Jadhav 2. Akash S. Phadatare 2. Snehal S. Shinde 2. Yuvraj R. Salvi

Volume/Issue: 02/03

Country: India

DOI NO.: 08.2020-25662434 DOI Link: https://www.doi-ds.org/doilink/09.2021-44567352/UIJIR

Affiliation:

1. Department of Plant Biotechnology, Rajiv Gandhi Institute of IT and Biotechnology, Bharati Vidyapeeth Deemed University, Pune-Satara Road, Pune, Maharashtra, India.
2. Department of Nanoscience and Technology, Yashavantrao Chavan Institute of Science, (Autonomous), Satara, Maharashtra, India.

ABSTRACT

Gymnema sylvestre is a well-known herb used in Ayurveda for its therapeutic uses. It is widely used in Diabetes mellitus as it possesses antidiabetic activity. The Indian Ayurveda describes several herbs for the management and treatment of Diabetes mellitus among which Gymnema sylvestre (Asclepiadaceae) is revered as a potential anti-diabetic herbal drug. Gymnema sylvestre also possesses anti-obesity, anti-hyperlipidemic, anti-inflammatory, and anti-cancerous activities. The phyto-constituents responsible for sweet suppression activity includes triterpene saponins known as gymnemic acids, gymnema saponins, and a polypeptide, gurmarin. This review article mainly focused on the traditionally used medicinal herb, Gymnema sylvestre, its bioactive components and its pharmacological activities.

Key words: Gymnema sylvestre, gymnemic acids, Diabetes mellitus, Antidiabetic