A REVIEW ARTICLE: POSSIBLE DISEASES THAT OCCUR DUE TO THE PRESENCE OF CHIMERAS IN THE HUMAN BODY

Author Name: 1. Zahraa S. M. Al Kaabi 2. Samah Amer Hammood 3. Ghofran F. Abdul Hassan 4. Lina A. Hassan

Volume/Issue: 04/02

Country: Iraq

DOI NO.: 08.2020-25662434 DOI Link: https://doi-ds.org/doilink/07.2023-35678912/UIJIR

Affiliation:

1. Faculty of Science, University of Kufa, Iraq.
2. Faculty of Science, University of Kufa, Iraq.

ABSTRACT

The existence of chimerism in human beings could potentially have various implications. The present review centers on the phenomenon of chimerism, with a particular emphasis on microchimerism, which represents a relatively unexplored avenue for elucidating variances in health and behavior. Male microchimerism in women is a phenomenon that is believed to occur due to fetomaternal exchange during pregnancy. This condition can be detected in women through the use of polymerase chain reaction molecular techniques that target Y-chromosomal markers. As a result, the examination of chimerism in human diseases has primarily concentrated on conditions that exhibit a higher incidence in females, such as autoimmune disorders and cancers affecting females. In this paper, we present an analysis of chimerism in various human diseases and explore potential behavioral implications. Comprehending the frequency of chimerism and its correlated health ramifications will furnish indispensable insight into human biology and direct innovative methods for managing illnesses.

Key words: Autoimmunity, Microchimerism, Chimera, Chimerism, Autoimmune diseases, Blood transfusions.