A COMPARATIVE STUDY TO ASSESS EFFECT OF DISCONTINUATION OF PROTON PUMP INHIBITORS (PPIs) AFTER 48 HOURS ON ADMISSION IN CRITICAL CARE UNIT ON INCIDENTS OF NOSOCOMIAL PNEUMONIA

Author Name: 1. Dr. Mahadeo B. Shinde 2. Ms. Besty Varghes

Volume/Issue: 03/05

Country: India

DOI NO.: 08.2020-25662434 DOI Link: https://www.doi-ds.org/doilink/11.2022-12746678/UIJIR

Affiliation:

1. Professor, Specialty of Medical-Surgical Nursing, Krishna Institute of Medical Nursing Sciences, Karad, India
2. Student, Krishna Institute of Medical Nursing Sciences, Karad, India

ABSTRACT

The aim of this study was to determine whether the use of gastric acid-suppressive agents increases the risk of nosocomial pneumonia (NP) in the Critical care unit population. The methodology adopted for experimenting with the effectiveness of the use of proton pump inhibitors in two study groups and evaluated the result with the help of APACHE II and CPIS calculator.The researcher performed an experimental study with a non-probability purposive sampling technique in a multi-critical care unit that included 60 critically ill patients fromJanuary 2021 to October 2021 at Krishna Hospital, Karad. The researcher divided patients into two groups after initiation of enteral feeding on a random basis, one group of patients with PPI and another group without PPI. Both of the groups were evaluated the risk of suspected HAI with the guidance of medical classification tools,APACHE-II, GCS, and CPIS at the time of admission and followed by consequent times irrespective of their diagnosis and treatment. There was no significant difference between the two groups for any of the scores (P>0.05) indicates very few cases of nosocomial pneumonia in Krishna hospital, Karad. In short, prior use of a proton-pump inhibitor did not correlate with a significant increase in the risk of developing Nosocomial Pneumonia (NP).Apart from Proton Pump Inhibitors, there are a plethora of treatments, nursing care received by critical care patients with various physical illnesses & symptoms. It is also important to treat different pre-disposing and existing clinical conditions because those factors affect the functional outcome of the patient. Further studies are required for more clarification related to correlating the effect of PPIs and early detection of HAI. For this, a standard group selection is suggested on matching diagnoses with similar hemodynamic status.

Key words: Proton Pump Inhibitor, Clinical pulmonary infection score, nosocomial pneumonia, Hospital-acquired infection, Acute Physiology and Chronic Health Evaluation score.